The Couch to 5K beginner's running schedule by Josh Clark at Cool Running has helped thousands of runners get off the couch and onto the roads, running 5K in 9 weeks. It is similar to the Learn to Run 5K (10 week program)

Because it is so well established there are a number of sites, supports and features that accompany the "C25K" plan. Some are specific to this plan,but some will be useful with any learn to run plan.

The Couch-to-5KRunning Plan

Podcasts for Running

Robert Ullrey's Assisted Workout and Training Mixes for your iPod
"Robert has recorded nine podcasts to accompany you on your runs. Some great music, plus Robert will tell you when to run, and when to walk...a must have."
Podrunner Intervals
"These free, varied-BPM workout music mixes for runners, joggers, and power walkers at all levels are designed to build endurance and improve overall conditioning"

• First Day to 5K - A 9-week course following the popular Couch to 5K template to get you started running even if you've never run before. Great if you're returning, too.
• Gateway to 8K - A 9-week course following the popular Couch to 5K template to get you started running even if you've never run before. Great if you're returning, too. 10 weeks to get you in shape for 8K runs. An excellent trainer to transition from 5K to 10K.
• Freeway to 10K - By the end of this 10-week series you'll be running a 10K or a solid 90 minutes.

Couch to 5K - Christian Indie Tracks

Apps

iPhone App
This app enables you to listen to your own music while it gives you audio cues when to switch from walking to running. It also has some other pretty cool features as well:
In app music player - enables you to change tracks without leaving the app (this feature requires iPhone OS 3.0 or greater)
Works with Nike+
Configure additional audio cues - like "halfway point", so you know when to turn back

Apps for Android mobile phone
This software accompanies the Couch to 5K aka C25K running plan from Cool Running.
It times your workout and let's you know through audio clips when it's time to switch your pace (from walking to running, or from running to cool-down for example) while listening to your own music or podcasts.
Keeps track of your progress - so you always know which workout is next
Share your workouts with your friends on Facebook and Twitter right from the app

Support

C25K Forums
A community of people helping each other achieve the goal of completing the Couch to 5K program.